Recent research has reported that proper dietary Intake of folate in young adulthood to be inversely associated with diabetes incidence in midlife among Americans. Researchers have published the findings in Diabetes Care. A recommendation supported by the American Diabetes Association is for women with preexisting diabetes to consume 400 micrograms of folic acid daily if they are capable of becoming pregnant, and to increase their consumption to 600 micrograms of folic acid daily if they are pregnant or planning to become pregnant.

Previous studies have shown homocysteine is associated with a higher risk of diabetes. Folate, which reduces homocysteine, is promising for the prevention and treatment of diabetes. Jie Zhu et al, associated with the Nutrition and Foods Program, Texas State University, had carried out a study to prospectively examine intakes of folate, vitamin B6, and vitamin B12 concerning diabetes incidence in a large U.S. cohort.

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